Diagnosis Mantle cell lymphoma diagnosis often begins with a physical exam that checks for swollen lymph nodes in the neck, underarms and groin. The exam also checks for a swollen spleen or liver. Other tests and procedures might include blood tests, imaging tests and taking a sample of tissue for lab testing.
https://www.mayoclinic.org/diseases-conditions/mantle-cell-lymphoma/diagnosis-treatment/drc-20584873