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Advancing reduction of drug use as an endpoint in addiction treatment …

December 13, 2025

This blog was also published in the American Society of Addiction Medicine (ASAM) Weekly on March 18, 2025. For many people trying to recover from a substance use disorder, perhaps for the majority, abstinence may be the most appropriate treatment objective. But complete abstinence is sometimes not achievable, even in the long-term, and there is a need for new treatment approaches that …

https://nida.nih.gov/about-nida/noras-blog/2025/03/advancing-reduction-drug-use-endpoint-in-addiction-treatment-trials

Advancing reduction of drug use as an endpoint in addiction treatment … <body> <h1> Array ( [0] => zdvancing reduction of drug use as an endpoint in addiction treatment … [1] => sdvancing reduction of drug use as an endpoint in addiction treatment … [2] => wdvancing reduction of drug use as an endpoint in addiction treatment … [3] => qdvancing reduction of drug use as an endpoint in addiction treatment … [4] => asvancing reduction of drug use as an endpoint in addiction treatment … [5] => axvancing reduction of drug use as an endpoint in addiction treatment … [6] => acvancing reduction of drug use as an endpoint in addiction treatment … [7] => afvancing reduction of drug use as an endpoint in addiction treatment … [8] => arvancing reduction of drug use as an endpoint in addiction treatment … [9] => aevancing reduction of drug use as an endpoint in addiction treatment … [10] => adcancing reduction of drug use as an endpoint in addiction treatment … [11] => adbancing reduction of drug 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treatment … [49] => advancing teduction of drug use as an endpoint in addiction treatment … [50] => advancing 5eduction of drug use as an endpoint in addiction treatment … [51] => advancing 4eduction of drug use as an endpoint in addiction treatment … [52] => advancing rwduction of drug use as an endpoint in addiction treatment … [53] => advancing rsduction of drug use as an endpoint in addiction treatment … [54] => advancing rdduction of drug use as an endpoint in addiction treatment … [55] => advancing rrduction of drug use as an endpoint in addiction treatment … [56] => advancing r4duction of drug use as an endpoint in addiction treatment … [57] => advancing r3duction of drug use as an endpoint in addiction treatment … [58] => advancing resuction of drug use as an endpoint in addiction treatment … [59] => advancing rexuction of drug use as an endpoint in addiction treatment … [60] => advancing recuction of drug use as an endpoint in addiction treatment … [61] => advancing refuction of drug use as an endpoint in addiction treatment … [62] => advancing reruction of drug use as an endpoint in addiction treatment … [63] => advancing reeuction of drug use as an endpoint in addiction treatment … [64] => advancing redyction of drug use as an endpoint in addiction treatment … [65] => advancing redhction of drug use as an endpoint in addiction treatment … [66] => advancing redjction of drug use as an endpoint in addiction treatment … [67] => advancing rediction of drug use as an endpoint in addiction treatment … [68] => advancing red8ction of drug use as an endpoint in addiction treatment … [69] => advancing red7ction of drug use as an endpoint in addiction treatment … [70] => advancing reduxtion of drug use as an endpoint in addiction treatment … [71] => advancing reduvtion of drug use as an endpoint in addiction treatment … [72] => advancing reduftion of drug use as an endpoint in addiction treatment … [73] => advancing redudtion of drug use as an endpoint in addiction treatment … [74] => advancing redudtion of drug use as an endpoint in addiction treatment … [75] => advancing reducrion of drug use as an endpoint in addiction treatment … [76] => advancing reducfion of drug use as an endpoint in addiction treatment … [77] => advancing reducgion of drug use as an endpoint in addiction treatment … [78] => advancing reducyion of drug use as an endpoint in addiction treatment … [79] => advancing reduc6ion of drug use as an endpoint in addiction treatment … [80] => advancing reduc5ion of drug use as an endpoint in addiction treatment … [81] => advancing reductuon of drug use as an endpoint in addiction treatment … [82] => advancing reductjon of drug use as an endpoint in addiction treatment … [83] => advancing reductkon of drug use as an endpoint in addiction treatment … [84] => advancing reductoon of drug use as an endpoint in addiction treatment … [85] => advancing reduct9on of drug use as an endpoint in addiction treatment … [86] => advancing reduct8on of drug use as an endpoint in addiction treatment … [87] => advancing reductiin of drug use as an endpoint in addiction treatment … [88] => advancing reductikn of drug use as an endpoint in addiction treatment … [89] => advancing reductiln of drug use as an endpoint in addiction treatment … [90] => advancing reductipn of drug use as an endpoint in addiction treatment … [91] => advancing reducti0n of drug use as an endpoint in addiction treatment … [92] => advancing reducti9n of drug use as an endpoint in addiction treatment … [93] => advancing reductiob of drug use as an endpoint in addiction treatment … [94] => advancing reductiom of drug use as an endpoint in addiction treatment … [95] => advancing reductioj of drug use as an endpoint in addiction treatment … [96] => advancing reductioh of drug use as an endpoint in addiction treatment … [97] => advancing reductioh of drug use as an endpoint in addiction treatment … [98] => advancing reduction if drug use as an endpoint in addiction 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use as an endpoint in addiction treatment … [124] => advancing reduction of drjg use as an endpoint in addiction treatment … [125] => advancing reduction of drig use as an endpoint in addiction treatment … [126] => advancing reduction of dr8g use as an endpoint in addiction treatment … [127] => advancing reduction of dr7g use as an endpoint in addiction treatment … [128] => advancing reduction of druf use as an endpoint in addiction treatment … [129] => advancing reduction of druv use as an endpoint in addiction treatment … [130] => advancing reduction of drub use as an endpoint in addiction treatment … [131] => advancing reduction of druh use as an endpoint in addiction treatment … [132] => advancing reduction of druy use as an endpoint in addiction treatment … [133] => advancing reduction of drut use as an endpoint in addiction treatment … [134] => advancing reduction of drug yse as an endpoint in addiction treatment … [135] => advancing reduction of drug hse as an endpoint in 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drug use ae an endpoint in addiction treatment … [161] => advancing reduction of drug use aw an endpoint in addiction treatment … [162] => advancing reduction of drug use as zn endpoint in addiction treatment … [163] => advancing reduction of drug use as sn endpoint in addiction treatment … [164] => advancing reduction of drug use as wn endpoint in addiction treatment … [165] => advancing reduction of drug use as qn endpoint in addiction treatment … [166] => advancing reduction of drug use as ab endpoint in addiction treatment … [167] => advancing reduction of drug use as am endpoint in addiction treatment … [168] => advancing reduction of drug use as aj endpoint in addiction treatment … [169] => advancing reduction of drug use as ah endpoint in addiction treatment … [170] => advancing reduction of drug use as ah endpoint in addiction treatment … [171] => advancing reduction of drug use as an wndpoint in addiction treatment … [172] => advancing reduction of drug use as an sndpoint in addiction treatment … [173] => advancing reduction of drug use as an dndpoint in addiction treatment … [174] => advancing reduction of drug use as an rndpoint in addiction treatment … [175] => advancing reduction of drug use as an 4ndpoint in addiction treatment … [176] => advancing reduction of drug use as an 3ndpoint in addiction treatment … [177] => advancing reduction of drug use as an ebdpoint in addiction treatment … [178] => advancing reduction of drug use as an emdpoint in addiction treatment … [179] => advancing reduction of drug use as an ejdpoint in addiction treatment … [180] => advancing reduction of drug use as an ehdpoint in addiction treatment … [181] => advancing reduction of drug use as an ehdpoint in addiction treatment … [182] => advancing reduction of drug use as an enspoint in addiction treatment … [183] => advancing reduction of drug use as an enxpoint in addiction treatment … [184] => advancing reduction of drug use as an encpoint in addiction treatment … [185] => advancing reduction of drug use as an enfpoint in addiction treatment … [186] => advancing reduction of drug use as an enrpoint in addiction treatment … [187] => advancing reduction of drug use as an enepoint in addiction treatment … [188] => advancing reduction of drug use as an endooint in addiction treatment … [189] => advancing reduction of drug use as an endloint in addiction treatment … [190] => advancing reduction of drug use as an end-oint in addiction treatment … [191] => advancing reduction of drug use as an end0oint in addiction treatment … [192] => advancing reduction of drug use as an endpiint in addiction treatment … [193] => advancing reduction of drug use as an endpkint in addiction treatment … [194] => advancing reduction of drug use as an endplint in addiction treatment … [195] => advancing reduction of drug use as an endppint in addiction treatment … [196] => advancing reduction of drug use as an endp0int in addiction treatment … [197] => advancing reduction of drug use as an endp9int in addiction treatment … [198] => advancing reduction of drug use as an endpount in addiction treatment … [199] => advancing reduction of drug use as an endpojnt in addiction treatment … [200] => advancing reduction of drug use as an endpoknt in addiction treatment … [201] => advancing reduction of drug use as an endpoont in addiction treatment … [202] => advancing reduction of drug use as an endpo9nt in addiction treatment … [203] => advancing reduction of drug use as an endpo8nt in addiction treatment … [204] => advancing reduction of drug use as an endpoibt in addiction treatment … [205] => advancing reduction of drug use as an endpoimt in addiction treatment … [206] => advancing reduction of drug use as an endpoijt in addiction treatment … [207] => advancing reduction of drug use as an endpoiht in addiction treatment … [208] => advancing reduction of drug use as an endpoiht in addiction treatment … [209] => advancing reduction of drug use as an endpoinr in addiction treatment … [210] => advancing reduction of drug use as an endpoinf in addiction treatment … [211] => advancing reduction of drug use as an endpoing in addiction treatment … [212] => advancing reduction of drug use as an endpoiny in addiction treatment … [213] => advancing reduction of drug use as an endpoin6 in addiction treatment … [214] => advancing reduction of drug use as an endpoin5 in addiction treatment … [215] => advancing reduction of drug use as an endpoint un addiction treatment … [216] => advancing reduction of drug use as an endpoint jn addiction treatment … [217] => advancing reduction of drug use as an endpoint kn addiction treatment … [218] => advancing reduction of drug use as an endpoint on addiction treatment … [219] => advancing reduction of drug use as an endpoint 9n addiction treatment … [220] => advancing reduction of drug use as an endpoint 8n addiction treatment … [221] => advancing reduction of drug use as an endpoint ib addiction treatment … [222] => advancing reduction of drug use as an endpoint im addiction treatment … [223] => advancing reduction of drug use as an endpoint ij addiction treatment … [224] => advancing reduction of drug use as an endpoint ih addiction treatment … [225] => advancing reduction of drug use as an endpoint ih addiction treatment … [226] => advancing reduction of drug use as an endpoint in zddiction treatment … [227] => advancing reduction of drug use as an endpoint in sddiction treatment … [228] => advancing reduction of drug use as an endpoint in wddiction treatment … [229] => advancing reduction of drug use as an endpoint in qddiction treatment … [230] => advancing reduction of drug use as an endpoint in asdiction treatment … [231] => advancing reduction of drug use as an endpoint in axdiction treatment … [232] => advancing reduction of drug use as an endpoint in acdiction treatment … [233] => advancing reduction of drug use as an endpoint in afdiction treatment … [234] => advancing reduction of drug use as an endpoint in ardiction treatment … [235] => advancing reduction of drug use as an endpoint in aediction treatment … [236] => advancing reduction of drug use as an endpoint in adsiction treatment … [237] => advancing reduction of drug use as an endpoint in adxiction treatment … [238] => advancing reduction of drug use as an endpoint in adciction treatment … [239] => advancing reduction of drug use as an endpoint in adfiction treatment … [240] => advancing reduction of drug use as an endpoint in adriction treatment … [241] => advancing reduction of drug use as an endpoint in adeiction treatment … [242] => advancing reduction of drug use as an endpoint in adduction treatment … [243] => advancing reduction of drug use as an endpoint in addjction treatment … [244] => advancing reduction of drug use as an endpoint in addkction treatment … [245] => advancing reduction of drug use as an endpoint in addoction treatment … [246] => advancing reduction of drug use as an endpoint in add9ction treatment … [247] => advancing reduction of drug use as an endpoint in add8ction treatment … [248] => advancing reduction of drug use as an endpoint in addixtion treatment … [249] => advancing reduction of drug use as an endpoint in addivtion treatment … [250] => advancing reduction of drug use as an endpoint in addiftion treatment … [251] => advancing reduction of drug use as an endpoint in addidtion treatment … [252] => advancing reduction of drug use as an endpoint in addidtion treatment … [253] => advancing reduction of drug use as an endpoint in addicrion treatment … [254] => advancing reduction of drug use as an endpoint in addicfion treatment … [255] => advancing reduction of drug use as an endpoint in addicgion treatment … [256] => advancing reduction of drug use as an endpoint in addicyion treatment … [257] => advancing reduction of drug use as an endpoint in addic6ion treatment … [258] => advancing reduction of drug use as an endpoint in addic5ion treatment … [259] => advancing reduction of drug use as an endpoint in addictuon treatment … [260] => advancing reduction of drug use as an endpoint in addictjon treatment … [261] => advancing reduction of drug use as an endpoint in addictkon treatment … [262] => advancing reduction of drug use as an endpoint in addictoon treatment … [263] => advancing reduction of drug use as an endpoint in addict9on treatment … [264] => advancing reduction of drug use as an endpoint in addict8on treatment … [265] => advancing reduction of drug use as an endpoint in addictiin treatment … [266] => advancing reduction of drug use as an endpoint in addictikn treatment … [267] => advancing reduction of drug use as an endpoint in addictiln treatment … [268] => advancing reduction of drug use as an endpoint in addictipn treatment … [269] => advancing reduction of drug use as an endpoint in addicti0n treatment … [270] => advancing reduction of drug use as an endpoint in addicti9n treatment … [271] => advancing reduction of drug use as an endpoint in addictiob treatment … [272] => advancing reduction of drug use as an endpoint in addictiom treatment … [273] => advancing reduction of drug use as an endpoint in addictioj treatment … [274] => advancing reduction of drug use as an endpoint in addictioh treatment … [275] => advancing reduction of drug use as an endpoint in addictioh treatment … [276] => advancing reduction of drug use as an endpoint in addiction rreatment … [277] => advancing reduction of drug use as an endpoint in addiction freatment … [278] => advancing reduction of drug use as an endpoint in addiction greatment … [279] => advancing reduction of drug use as an endpoint in addiction yreatment … [280] => advancing reduction of drug use as an endpoint in addiction 6reatment … [281] => advancing reduction of drug use as an endpoint in addiction 5reatment … [282] => advancing reduction of drug use as an endpoint in addiction teeatment … [283] => advancing reduction of drug use as an endpoint in addiction tdeatment … [284] => advancing reduction of drug use as an endpoint in addiction tfeatment … [285] => advancing reduction of drug use as an endpoint in addiction tteatment … [286] => advancing reduction of drug use as an endpoint in addiction t5eatment … [287] => advancing reduction of drug use as an endpoint in addiction t4eatment … [288] => advancing reduction of drug use as an endpoint in addiction trwatment … [289] => advancing reduction of drug use as an endpoint in addiction trsatment … [290] => advancing reduction of drug use as an endpoint in addiction trdatment … [291] => advancing reduction of drug use as an endpoint in addiction trratment … [292] => advancing reduction of drug use as an endpoint in addiction tr4atment … [293] => advancing reduction of drug use as an endpoint in addiction tr3atment … [294] => advancing reduction of drug use as an endpoint in addiction treztment … [295] => advancing reduction of drug use as an endpoint in addiction trestment … [296] => advancing reduction of drug use as an endpoint in addiction trewtment … [297] => advancing reduction of drug use as an endpoint in addiction treqtment … [298] => advancing reduction of drug use as an endpoint in addiction trearment … [299] => advancing reduction of drug use as an endpoint in addiction treafment … [300] => advancing reduction of drug use as an endpoint in addiction treagment … [301] => advancing reduction of drug use as an endpoint in addiction treayment … [302] => advancing reduction of drug use as an endpoint in addiction trea6ment … [303] => advancing reduction of drug use as an endpoint in addiction trea5ment … [304] => advancing reduction of drug use as an endpoint in addiction treatnent … [305] => advancing reduction of drug use as an endpoint in addiction treatkent … [306] => advancing reduction of drug use as an endpoint in addiction treatjent … [307] => advancing reduction of drug use as an endpoint in addiction treatjent … [308] => advancing reduction of drug use as an endpoint in addiction treatmwnt … [309] => advancing reduction of drug use as an endpoint in addiction treatmsnt … [310] => advancing reduction of drug use as an endpoint in addiction treatmdnt … [311] => advancing reduction of drug use as an endpoint in addiction treatmrnt … [312] => advancing reduction of drug use as an endpoint in addiction treatm4nt … [313] => advancing reduction of drug use as an endpoint in addiction treatm3nt … [314] => advancing reduction of drug use as an endpoint in addiction treatmebt … [315] => advancing reduction of drug use as an endpoint in addiction treatmemt … [316] => advancing reduction of drug use as an endpoint in addiction treatmejt … [317] => advancing reduction of drug use as an endpoint in addiction treatmeht … [318] => advancing reduction of drug use as an endpoint in addiction treatmeht … [319] => advancing reduction of drug use as an endpoint in addiction treatmenr … [320] => advancing reduction of drug use as an endpoint in addiction treatmenf … [321] => advancing reduction of drug use as an endpoint in addiction treatmeng … [322] => advancing reduction of drug use as an endpoint in addiction treatmeny … [323] => advancing reduction of drug use as an endpoint in addiction treatmen6 … [324] => advancing reduction of drug use as an endpoint in addiction treatmen5 … [325] => advancing reduction of drug use as an endpoint in addiction treatment ᰾ [326] => advancing reduction of drug use as an endpoint in addiction treatment &#u230; [327] => advancing reduction of drug use as an endpoint in addiction treatment &#i230; [328] => advancing reduction of drug use as an endpoint in addiction treatment ␎ [329] => advancing reduction of drug use as an endpoint in addiction treatment ῂ [330] => advancing reduction of drug use as an endpoint in addiction treatment &#8q30; [331] => advancing reduction of drug use as an endpoint in addiction treatment &#8w30; [332] => advancing reduction of drug use as an endpoint in addiction treatment ₊ [333] => advancing reduction of drug use as an endpoint in addiction treatment “ [334] => advancing reduction of drug use as an endpoint in addiction treatment &#82w0; [335] => advancing reduction of drug use as an endpoint in addiction treatment &#82e0; [336] => advancing reduction of drug use as an endpoint in addiction treatment ‰ [337] => advancing reduction of drug use as an endpoint in addiction treatment   [338] => advancing reduction of drug use as an endpoint in addiction treatment &#823o; [339] => advancing reduction of drug use as an endpoint in addiction treatment &#823p; [340] => advancing reduction of drug use as an endpoint in addiction treatment &#823-; [341] => advancing reduction of drug use as an endpoint in addiction treatment &#8230l [342] => advancing reduction of drug use as an endpoint in addiction treatment &#8230p [343] => advancing reduction of drug use as an endpoint in addiction treatment &#8230. ) </h1> </body>